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Adenosine Deaminases Acting on RNA (Adars) and A-To-I Editing 2012 Edition Contributor(s): Samuel, Charles E. (Editor) |
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ISBN: 3642228003 ISBN-13: 9783642228001 Publisher: Springer
Binding Type: Hardcover - See All Available Formats & Editions Published: November 2011 Click for more in this series: Current Topics in Microbiology and Immmunology |
Additional Information |
BISAC Categories: - Science | Life Sciences - Molecular Biology - Medical | Physiology - Medical | Anatomy |
Dewey: 611.018 |
Series: Current Topics in Microbiology and Immmunology |
Physical Information: 0.9" H x 6.3" W x 9.1" L (1.05 lbs) 238 pages |
Descriptions, Reviews, Etc. |
Publisher Description: "The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins." |
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