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Adherens Junctions: From Molecular Mechanisms to Tissue Development and Disease 2012 Edition
Contributor(s): Harris, Tony (Editor)

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 ISBN: 9400796161     ISBN-13: 9789400796164
Publisher: Springer
OUR PRICE: $208.99  

Binding Type: Paperback - See All Available Formats & Editions
Published: July 2014
Qty:

Click for more in this series: Subcellular Biochemistry
Additional Information
BISAC Categories:
- Medical | Oncology - General
- Science | Life Sciences - Biochemistry
- Science | Life Sciences - Molecular Biology
Dewey: 571.6
Series: Subcellular Biochemistry
Physical Information: 0.89" H x 6.14" W x 9.21" L (1.35 lbs) 434 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Cell-cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development. AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases. This book addresses major questions encompassing AJ biology.
- How did AJs evolve?
- How do cadherins and catenins interact to assemble AJs and mediate adhesion?
- How do AJs interface with other cellular machinery to couple adhesion with the whole cell?
- How do AJs affect cell behaviour and multicellular development?
- How can abnormal AJ activity lead to disease?
 
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