Introduction to Peptides and Proteins Contributor(s): Langel, Ulo (Author), Cravatt, Benjamin F. (Author), Graslund, Astrid (Author) |
|||
ISBN: 1420064126 ISBN-13: 9781420064124 Publisher: CRC Press
Binding Type: Hardcover - See All Available Formats & Editions Published: November 2009 Annotation: Authored by key players in the field, this volume offers a relevant presentation of peptide and protein chemistry. It provides key insight into the fast-developing field of proteomics, including structural and functional aspects, biochip development, and clinical potential. The authors include chapters on bioinformatics and proteomics and present the latest information on concerns over protein degradation and the post-translational modifications of proteins and peptides. The book also includes a section on "protein coupled diseases" that presents increasing evidence of the impact of protein misfolding and various deviations in neurodegenerative diseases, and the role of proteins in cancer. |
Additional Information |
BISAC Categories: - Science | Life Sciences - Biochemistry - Medical | Biochemistry - Science | Life Sciences - Cell Biology |
Dewey: 572.65 |
LCCN: 2009028736 |
Physical Information: 1.1" H x 6.4" W x 9.3" L (1.65 lbs) 438 pages |
Features: Bibliography, Illustrated, Index, Table of Contents |
Review Citations: Scitech Book News 03/01/2010 pg. 60 |
Descriptions, Reviews, Etc. |
Publisher Description: Human cells produce at least 30,000 different proteins. Each has a specific function characterized by a unique sequence and native conformation that allows it to perform that function. While research in this post-genomic era has created a deluge of invaluable information, the field has lacked for an authoritative introductory text needed to inform researchers and students in all of those fields now concerned with protein research. Introduction to Peptides and Proteins brings together some of the most respected researchers in protein science to present a remarkably coherent introduction to modern peptide and protein chemistry. The first sections of the book delve into -
After providing a foundation in tools and methods, the authors closely examine six protein families, including representative classes such as enzymes, cell-surface receptors, antibodies, fibrous proteins, and bioactive peptide classes. They concentrate on biochemical mechanisms and where possible indicate therapeutic or biotechnical possibilities. Then focusing on clinical aspects, the authors investigate misfolding as found in prion diseases, miscleavage as found in Alzheimer's, and mis-sequencing as found with some cancers. Drawing from some of their own research, the authors summarize recent achievements and emerging applications. They discuss the use of proteins and peptides as drugs and the solid-phase synthesis required for drug production. They also look at the use of peptides as functional biomolecules and research tools. No longer just th |
Customer ReviewsSubmit your own review |
To tell a friend about this book, you must Sign In First! |