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Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism: Volume 542
Contributor(s): Galluzzi, Lorenzo, Kroemer, Guido

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 ISBN: 0124166180     ISBN-13: 9780124166189
Publisher: Academic Press
OUR PRICE: $208.95  

Binding Type: Hardcover - See All Available Formats & Editions
Published: May 2014
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Temporarily out of stock - Will ship within 2 to 5 weeks

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Additional Information
BISAC Categories:
- Medical | Oncology - General
- Science | Life Sciences - Biochemistry
- Science | Life Sciences - Genetics & Genomics
Dewey: 616.994
Series: Methods in Enzymology
Physical Information: 1.2" H x 6.1" W x 9.1" L (2.30 lbs) 536 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as yet another general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.
 
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