Power Search
Low Price Guarantee
We Take School POs
Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis 2019 Edition
Contributor(s): Kale, Avinash (Editor)

View larger image

 ISBN: 981137449X     ISBN-13: 9789811374494
Publisher: Springer
OUR PRICE: $104.49  

Binding Type: Hardcover - See All Available Formats & Editions
Published: November 2019
Qty:
Additional Information
BISAC Categories:
- Medical | Parasitology
- Sports & Recreation
- Science | Life Sciences - Biochemistry
Dewey: 570.285
Physical Information: 0.31" H x 6.14" W x 9.21" L (0.75 lbs) 101 pages
 
Descriptions, Reviews, Etc.
Publisher Description:

This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements.

The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13-24 as potential drug targets against malaria. As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design.

Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.

 
Customer ReviewsSubmit your own review
 
To tell a friend about this book, you must Sign In First!