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Accounts in Drug Discovery: Case Studies in Medicinal Chemistry
Contributor(s): Barrish, Joel (Editor), Carter, Percy (Editor), Cheng, Peter (Editor)

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 ISBN: 1849731268     ISBN-13: 9781849731263
Publisher: Royal Society of Chemistry
OUR PRICE: $176.70  

Binding Type: Hardcover
Published: September 2010
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Additional Information
BISAC Categories:
- Science | Chemistry - Clinical
- Medical | Pharmacology
- Science | Chemistry - Organic
Dewey: 615.19
Series: RSC Drug Discovery
Physical Information: 1.06" H x 6.39" W x 9.37" L (1.56 lbs) 370 pages
Features: Bibliography, Illustrated, Index, Table of Contents
 
Descriptions, Reviews, Etc.
Publisher Description:
Accounts in Drug Discovery describes recent case studies in drug discovery and in particular how problems were overcome. In particular, the case studies were selected to cover a broad range of topics including: diverse disease areas (oncology, cardiovascular, metabolic disorders, inflammation, anti-infective agents, GI and urinary disorders); first-in-class vs. follow on compounds; leads compounds that were derived from multiple sources including screening, structure-based design, and follow-ons; successful marketed drugs as well as those that failed prior to or at registration that are rarely communicated in such a compendium. The issues to be addressed, both in Discovery and in the Clinic, will survey those commonly faced by researchers in the field including: metabolism and pharmacokinetics, toxicology, pharmaceutics, and proof of concept for the biological target.
 
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