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The Glutamate Synapse as a Therapeutic Target: Volume 116
Contributor(s): Ottersen, O. P., Langmoen, I. a., Gjerstad, L.

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ISBN: 0444827544     ISBN-13: 9780444827548
Publisher: Elsevier Science
OUR PRICE: $289.75  

Binding Type: Hardcover - See All Available Formats & Editions
Published: November 1998
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Annotation: This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.

A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation.

Additional Information
BISAC Categories:
- Medical | Neurology
- Medical | Neuroscience
- Science | Life Sciences - Neuroscience
Dewey: 616.804
LCCN: 98029333
Physical Information: 462 pages
Features: Bibliography, Illustrated, Index
 
Descriptions, Reviews, Etc.
Publisher Description:
This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.


A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation.

 
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