The Glutamate Synapse as a Therapeutic Target: Volume 116 Contributor(s): Ottersen, O. P., Langmoen, I. a., Gjerstad, L. |
|||
ISBN: 0444827544 ISBN-13: 9780444827548 Publisher: Elsevier Science
Binding Type: Hardcover - See All Available Formats & Editions Published: November 1998 Annotation: This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation. |
Additional Information |
BISAC Categories: - Medical | Neurology - Medical | Neuroscience - Science | Life Sciences - Neuroscience |
Dewey: 616.804 |
LCCN: 98029333 |
Physical Information: 462 pages |
Features: Bibliography, Illustrated, Index |
Descriptions, Reviews, Etc. |
Publisher Description: This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.
|
Customer ReviewsSubmit your own review |
To tell a friend about this book, you must Sign In First! |