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System Modeling in Cellular Biology: From Concepts to Nuts and Bolts
Contributor(s): Szallasi, Zoltan (Editor), Stelling, Jörg (Editor), Periwal, Vipul (Editor)

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ISBN: 0262195488     ISBN-13: 9780262195485
Publisher: MIT Press
OUR PRICE: $9.49  

Binding Type: Hardcover - See All Available Formats & Editions
Published: March 2006
* Out of Print *

Annotation: Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds. The emerging area of systems level modeling in cellular biology has lacked a critical and thorough overview. This book fills that gap. It is the first to provide the necessary critical comparison of concepts and approaches, with an emphasis on their possible applications. It presents key concepts and their theoretical background, including the concepts of robustness and modularity and their exploitation to study biological systems; the best-known modeling approaches, and their advantages and disadvantages; lessons from the application of mathematical models to the study of cellular biology; and available modeling tools and datasets, along with their computational limitations.

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Additional Information
BISAC Categories:
- Computers | Computer Science
Dewey: 571.601
LCCN: 2005054539
Age Level: 18-UP
Grade Level: 13-UP
Series: Mit Press
Physical Information: 1.06" H x 7.18" W x 9.28" L (1.97 lbs) 448 pages
Features: Bibliography, Dust Cover, Illustrated, Index, Table of Contents
 
Descriptions, Reviews, Etc.
Publisher Description:

An introduction and overview of system modeling in biology that is accessible to researchers from different fields, including biology, computer science, mathematics, statistics, physics, and biochemistry.

Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds.

The emerging area of systems level modeling in cellular biology has lacked a critical and thorough overview. This book fills that gap. It is the first to provide the necessary critical comparison of concepts and approaches, with an emphasis on their possible applications. It presents key concepts and their theoretical background, including the concepts of robustness and modularity and their exploitation to study biological systems; the best-known modeling approaches, and their advantages and disadvantages; lessons from the application of mathematical models to the study of cellular biology; and available modeling tools and datasets, along with their computational limitations.


Contributor Bio(s): Periwal, Vipul: - Vipul Periwal is with the Mathematical Cell Modeling Section, NIDDK, National Institute of Health.Szallasi, Zoltan: - Zoltan Szallasi is Professor at the Center for Biological Sequence Analysis, Technical University of Denmark.Stelling, Jorg: - Jörg Stelling is a faculty member of the Department of Biosystems Science and Engineering at ETH Zürich.
 
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